Publishchemidea, 2014 No: 10
Submitted: Wednesday, April 2nd, 2014
| Title of the idea: |
Synthesis of Benzyl pyridines |
| Author of the idea: |
holladc |
| Email of the author |
rlfcrd@hotmail.com |
| Key words for search: |
Pyridine, phenylaceticacid, sodium acetate |
| Explain briefly the idea |
Phenyl acetic acid is used as benzyl equivalent in the literature. However this has not been exploited for the synthesis of benzyl pyridines. This method provides an easy access to synthesis of 2/4 benzyl pyridines. One can also try using 2-bromo pyridines
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| Why do you think this idea will work? |
In synthesis of pharmaceutically active intermediates like 2-benzoylpyridines |
| Do you have any experimental proof? |
No |
| Literature reference |
R. Weiss, OSCV 2, 1943, p61 , J. Bernstein etal, USpatent: 3052721, 1962 |
| Where it is useful? |
Academic |
| Do you plan to work on this idea in near future? |
Yes |
| Interested in collaboration? |
Yes |
| Nature of idea: |
Theoretical/experimental |
| Youtube link: |
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