Publishchemidea, 2014 No: 8
Submitted: Friday, February 7th, 2014
| Title of the idea: |
Intramolecular hydroxylation of Allylic N-Oxides |
| Author of the idea: |
Ramesha |
| Email of the author |
ramesha63@hotmail.com |
| Key words for search: |
Dihydroxylation, Osmium tetroxide, N-Oxide, Hydrogen peroxide |
| Explain briefly the idea |
Sharpless dihydroxylation is normally done with N-Oxide and OsO4 in water. This can be extended to intramolecular dihydroxylation as represented. Sharpless epoxidation withallylic hydroperoxides is already known. But allylic N-oxide to dihydroxylation is not reported so far.
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| Why do you think this idea will work? |
Dihydroxylation of allylic or non allylic olefins of tert amines. |
| Do you have any experimental proof? |
No |
| Literature reference |
V. Van Rheenen, D. Y. Cha, W. M. Hartler, OSCV 6, 1988, P342 |
| Where it is useful? |
Academic |
| Do you plan to work on this idea in near future? |
Yes |
| Interested in collaboration? |
Yes |
| Nature of idea: |
Theoretical/experimental |
| Youtube link: |
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