Publishchemidea, 2016 No: 18
Submitted: Wednesday, January 20th, 2016
| Title of the idea: |
Interconversion of aromatic halides -Electrophillic iodination of Grignard reagent |
| Author of the idea: |
Ramesha |
| Email of the author |
ramesha63@hotmail.com |
| Key words for search: |
CHloro, Iodo, bromo, aryl, Grignard |
| Explain briefly the idea |
Conversion of aromatic chloride or Bromide to aromatic Iodo compounds is difficult to achieve. Bromo to Iodo is done by reacting with CuI in DMF/DMSO. However, chloro to Iodo conversion is difficult. This method provides an interesting way of reacting Grignard reagent with Iodine (electrophile equivalent). If works, will be an interesting synthetic method in Organic synthesis.
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| Why do you think this idea will work? |
We have carried out bromo to Iodo in the laboratiry in 50 g scale. It works! |
| Do you have any experimental proof? |
Yes. NMR Data |
| Literature reference |
No |
| Where it is useful? |
WIll be useful both in industry and academia |
| Do you plan to work on this idea in near future? |
No |
| Interested in collaboration? |
Yes |
| Nature of idea: |
Synthetic organic chemistry |
| Youtube link: |
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