Publishchemidea, 2020 No: 25
Submitted: Thursday, July 23rd, 2020
| Title of the idea: |
Michel addition followed by Dipolar cycloaddition in one pot |
| Author of the idea: |
Ramesha |
| Email of the author |
ramesha63@hotmail.com |
| Key words for search: |
Diamino alcohol, Michel addition, Cycloaddition, Chloramine-T, nitro olefine |
| Explain briefly the idea |
Chloramine-T can undergo Michel addition with unsaturated nitro compound. The intermediate thus obtained can be trapped with an olefin by dipolar cycloaddition. The product thus formed can be converted to diamino alcohol. Reaction can be done at 70-100 degree centigrade in diglyme or DMF/DMSO.
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| Why do you think this idea will work? |
Chemistry looks feasible |
| Do you have any experimental proof? |
No |
| Literature reference |
No |
| Where it is useful? |
Both industrially and academically |
| Do you plan to work on this idea in near future? |
No |
| Interested in collaboration? |
No |
| Nature of idea: |
Academic |
| Youtube link: |
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